DNAdamageresponse相关论文
PARP-1 inhibitors enhance the chemosensitivity of leukemia cells by attenuating NF-κB pathway activi
Idarubicin(IDA),an anthracycline antineoplastic drug,is commonly used in the treatment of acute myeloid leu-kemia(AML)wi......
cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senesce
As a sensor of cytosolic DNA,the role of cyclic GMP-AMP synthase (cGAS) in innate immune response is well established,ye......
Alterations of DNA damage response pathway:Biomarker and therapeutic strategy for cancer immunothera
Genomic instability remains an enabling feature of cancer and promotes malignant transfor-mation.Alterations of DNA dama......
Objective Idarubicin(IDA)is an anthracycline antineoplastic drug commonly used in acute myeloid leukemia.It has good cli......
Silica nanoparticles exposure inducing granulosa cell apoptosis and follicular atresia in female Bal
Given that the effects of ultrafine fractions(...
p53 shows stimulus-dependent dynamics in the DNA damage response,and the dynamic modes of p53 is linked closely with the......
In vertebratedefinitive hematopoiesis, nascent hematopoietic stem/progenitor cells(HSPCs) migrate to and reside in proli......
DNA-PKcs is an important molecule of non-homologous end joining repair of double strand breaks.Once DNA double strand br......
Tumor suppressor p53 restricts the proliferation of abnormal or DNA-damaged cells by regulating the expression of variou......
Comparative proteomic analysis of cisplatin-and oxaliplatininduced phosphorylation in proteins bound
Cisplatin and oxaliplatin are widely used chemotherapeutic agents with different anti-tumor spectra.[1] Cisplatin is bel......
Cisplatin,one of the most common anticancer drugs,binds to DNA and forms platinum-DNA crosslinks,leading to partial unwi......
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Long non-coding RNAs(lncRNAs) are increasingly involved in diverse biological processes. Upon DNA damage, the DNA damage......
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Objective: RECQL4 (a member of the RECQ helicase family) upregulation has been reported to be associated with tumor prog......
PIG3 (p53 可诱导的基因 3 ) ，原来作为 p53 在 apoptosis 的发作前导致的一套基因之一识别了，被假定贡献早细胞的反应到 DNA 损坏。......
DNA damage is a relatively common event in eukaryotic cell and may lead to genetic mutation and even cancer. DNA damage ......
Ataxia telangiectasia-mutated-Rad3-related DNA damage checkpoint signaling pathway triggered by hepa
AIM: To explore whether acute cellular DNA damage response is induced upon hepatitis B virus (HBV) infection and the eff......
